-
246
Enhanced Antitumor Efficacy and Reduced Myelosuppression by a Supramolecular Complex Composed of Azocalix[4]arene and Sunitinib, Jing Liu#, Fangqian Yin#, Yanbin Ren, Mengqiong Ming, Houhuan Xie, Xin Cai, Juan-Juan Li*, Dong-Sheng Guo*, and Ke-Rang Wang*, J. Med. Chem., 2025, DOI: 10.1021/acs.jmedchem.5c02487.
-
245
Ultrahigh-Affinity 1:1 and 1:2 Molecular Recognition in Water by a Rim-Carboxylated Chiral Corral[4]BINOL, Li-Bo Jing, Ruiguo Wang, Rong Fu, Hui-Tao Zheng, Jin-Lei Zhou, Qing-Yu Zhao, Zi-Hang Song, Dong-Sheng Guo and Kang Cai*, Sci. China Chem., 2025, DOI: 10.1007/s11426-025-3065-2.
-
244
The rise and promise of macrocyclic hosts in biomedicine, Yu-Chen Pan, Jia-Xuan Li, Dong-Sheng Guo*, ACS Cent. Sci., 2025, DOI: 10.1021/acscentsci.5c00891.
-
243
Chiral macrocycles forming high-affinity host-guest homoternary complexes for chiral discrimination and amplified circularly polarized luminescence, Rong Fu, Fang-Yuan Chen, Le Dai, Dai-Yuan Li, Qing-Yu Zhao, Si-Dan Guo, Zi-Hang Song, Li-Bo Jing, Heng Wang, Xiaopeng Li, Dong-Sheng Guo, Kang Cai*, Nat. Commun., 2025, 16, 9718.
-
242
A Single-Molecule Pleuripotent Scaffold for Combinational Therapy of Alzheimer’s Disease via Intranasal Administration, Jian-Mei Gao#, Wen-Bo Li#, Na-Na Chen#, Yang Yi, Ze-Han Wang, Xian Chen, Yang-Yang Zhao, Ze-Li Yuan, Jie Gao, Yu-Chen Pan, Dong-Sheng Guo* and Qi-Hai Gong*, Adv. Sci., 2025, DOI: 10.1002/advs.202511611.
-
241
Corral[n]bicarbazoles: Redox-active Chiral Macrocycles for Air-stable Radical Cations Formation and Guest Capture/Release, Ruiguo Wang#, Han Han#*, Li-Bo Jing, Peng-Yao Shen, Xiao, Xiao, Jia-Ying Deng, Qi Zhang, Haiting Di, Dong-Sheng Guo, Kang Cai*, Angew. Chem. Int. Ed., 2025, 64, e202511366.
-
240
Architecting X-Aggregates as Charge Transport Pathways to Enhance Photocatalytic Activity of Metal–Organic Frameworks, Ru-Yi Li#, Wen-Ting Li#, Han-Fei Fu, Fang-Yuan Chen, Xiu-Zhen Wang, Wei-Yan Chen, Yue Li*, and Dong-Sheng Guo, Small, 2025, 21, 2505216.
-
239
Multiple Host-Guest Interactions in Metal-Organic Frameworks Constructed by Inverted Calix[4]arenes, Zongsu Han#, Kun-Yu Wang#, Yifan Guo, Ze-Han Wang, Rong-Ran Liang, Yihao Yang, Jiatong Huo, Dong-Sheng Guo* and Hong-Cai Zhou*, J. Am. Chem. Soc., 2025, 147, 25162–25166.
-
238
Highly Sensitive, Specific and Fast Fluorescent Sensing of Amphetamine via Structural Regulation, Sifan Cao, Yuan Liu*, Yanan Guo, Baiyi Zu, Fei Yan, Dong-Sheng Guo*, and Xincun Dou*, ACS Sens., 2025, 10, 1998–2006.
-
237
Rapid Detection of Zeranol Contamination in Cereals Using a Quaternary Ammonium-Functionalized Terphen[3]arene-Based Optical Sensor, Danni Wang#, Mengyu Ye#, Huijuan Yu, Kejing Niu, Chunju Li, Dong-Sheng Guo*, and Yuefei Wang*, Foods, 2025, 14, 863.
-
236
Macrocycle-containing metal-organic frameworks in adsorption and related applications, Hui-Qing Zhao, Yue Li*, Chunju Li* and Dong-Sheng Guo*, J. Mater. Chem. A, 2025, 13, 23354-23376.
-
235
Ophthalmic formulation of methotrexate: a strategy of using the self-assembled LacAC4A nanoparticles for non-invasive drug delivery to the ocular posterior segment, Xiao-Yun Hou#, Xiao-Ling Zhang#, An-Kang Ying#, Yu-Xin Yue, Tao Yang, Dong-Sheng Guo & Zhi-Qing Li*, Drug Delivery, 2025, 32, 2509962.
-
234
Macrocycle-Engineered Liposomes for Combating Bacterial Biofilm Infections, Tian-Xing Zhang#*, Shiyu Peng#, Shu-Xin Zhang#, Yutong Xue, Linzhu Su, Fang-Yuan Chen, Jie Gao, Qingxiang Guo, Jianfeng Liu*, Fan Huang*, and Dong-Sheng Guo*, Chem. Eng. J., 2025, 518, 164500.
-
233
Hypoxia-sensitive macrocycle inclusion complexes for targeted protein degradation, Jiachan Lin#, Wenyan Wang#, An-Kang Ying#, Zirui Chen, Dan Zhang, Chendi Ding, Xiaowei Zeng*, Dong-Sheng Guo* and Hongzhong Chen*, J. Control. Release, 2025, 384, 113921.
-
232
Single-molecule Macrocyclic Carrier Overcomes the Direct Transmembrane of Medium-sized Cargoes, Xiaoxue Hou, Xin-Yue Hu*, Yang Wang, Huan-Yu Wang, Yu-Chen Pan, Jie Chen, Juan-Juan Li, Ze-Han Wang, Fan Huang*, Jianfeng Liu*, Dong-Sheng Guo*, J. Am. Chem. Soc., 2025, 147, 20919-20929.
-
231
Acid-tolerant and hypoxia-responsive drug delivery system based on sulphobetaine-modified azocalix[4]arene for treating ulcerative colitis, Jing Liu#, Juan-Juan Li#, Hai-Qing Li, Meiqi Yang, Kai Zhang, Fangqian Yin,Yanbin Ren, Mengqiong Ming, Dong-Sheng Guo* and Ke-Rang Wang*, Nano Today, 2025, 64, 102801.
-
230
α-Synuclein targeted therapy with multiple pathological improvement for Parkinson's disease by macrocyclic amphiphile nanomedicine, Jian-Mei Gao#, Wen-Bo Li#, Yang Yi, Jia-Jia Wei, Miao-Xian Gong, Bin-Bin Pan, Xun-Cheng Su, Yu-Chen Pan*, Dong-Sheng Guo* and Qi-Hai Gong*, Biomaterials, 2025, 322, 123378.
-
229
Ultrahigh-Affinity Molecular Recognition in Water and Biomedical Applications, Fang-Yuan Chen#, Rong Fu#, Zhihao Gong, Chunju Li*, Dong-Sheng Guo*, and Kang Cai*, Angew. Chem. Int. Ed., 2025, 64, e202500916.
-
228
Integrating Proteolysis-Targeting Chimeras (PROTACs) with Delivery Systems for More Efficient and Precise Targeted Protein Degradation, Jiachan Lin, Zirui Chen, Dan Zhang, Nan Zhang, Hongzhong Chen*, and Dong-Sheng Guo*, Macromol. Rapid Commun., 2025, 46, 2401051.
-
227
Tubular Chiral Molecular Carbon Imides, Ruiguo Wang, Li-Bo Jing, Jia-Ying Deng, Han Han, Rong Fu, Fang-Yuan Chen, Dong-Sheng Guo, Kang Cai*, CCS Chem., 2025, DOI: 10.31635/ccschem.025.202505572.
-
226
Controllable Ultrahigh-Affinity Molecular Recognition, Fang-Yuan Chen#, Han-Fang Zhang#, Kang Cai* and Dong-Sheng Guo*, Supramol. Mater., 2025, 4, 100101.
-
225
High-affinity 1:2 recognition based on naphthyl-azocalix[4]arene and its application as a cleavable noncovalent connector in constructing responsive supramolecular polymeric materials, Shun-Yu Yao#, An-Kang Ying#, Wen-Chao Geng, Fang-Yuan Chen, Xin-Yue Hu, Kang Cai*, Dong-Sheng Guo*, Chem. Sci., 2025, 16, 7066-7076.
-
224
A Supramolecular Biofilm Disruptor Based on Cationic Macrocyclic Amphiphiles to Eradicate Bacterial Biofilm-Associated Infections, Shiyu Peng#, Linzhu Su#,*, Er-Wei Zhang, Xiaoxue Hou, Qingxiang Guo, Ning Zhu, Tian-Xing Zhang*, Dong-Sheng Guo*, Jianfeng Liu* and Fan Huang*, Chem. Eng. J., 2025, 508, 160905.
-
223
Chiral Covalent Organic Cages: Construction and Chiral Functions, Si-Dan Guo, Tianyu Jiao, Dong-Sheng Guo*, and Kang Cai*, Smart Molecules, 2025, 3, e20240038.
-
222
Fluorescent discrimination for snake venom via a dual-mode supramolecular sensor array, Han-Wen Tian, Jia-Hong Tian, Xin-Yue Hu*, and Dong-Sheng Guo*, Pure. Appl. Chem., 2025, DOI: 10.1515/pac-2024-0320.
-
221
Vesicle-Encapsulated Chemosensing Ensembles Allow Monitoring of Transmembrane Uptake Coupled with Enzymatic Reactions, Ruixue Jiang, Mohamed Nilam, Claudio Piselli, Mathias Winterhalter, Dong-Sheng Guo, Sin-Yi Yu, Andreas Hennig*, Werner M. Nau*, Angew. Chem. Int. Ed., 2025, 64, e202425157.
-
220
Engineered hypoxia-responsive albumin nanoparticles mediating mitophagy regulation for cancer therapy, Wenyan Wang#, Shun-Yu Yao#, Jingjing Luo, Chendi Ding, Qili Huang, Yao Yang, Zhaoqing Shi, Jiachan Lin, Yu-Chen Pan, Xiaowei Zeng*, Dong-Sheng Guo*, Hongzhong Chen*, Nat. Commun., 2025, 16, 596.
-
219
Macrocycle-based differential sensing: design strategies and applications, Jia-Hong Tian, Zhe Zheng, Yu-Chen Pan*, Yuefei Wang*, and Dong-Sheng Guo*, Responsive Mater., 2025, 3, e20240036.
-
218
A FRET Autophagy Imaging Platform by Macrocyclic Amphiphile, Ze-Tao Jiang#, Jie Chen#, Fang-Yuan Chen#, Yuan-Qiu Cheng, Shun-Yu Yao, Rong Ma, Wen-Bo Li, Hongzhong Chen*, and Dong-Sheng Guo*, Angew. Chem. Int. Ed., 2025, 64, e202420793.
-
217
Enantiopure Macrocycles Based on Tröger's Base and Diphenyl Maleimide Exhibiting Strong Chiral Emission and Host-guest Properties, Zi-Hang Song, Yi-Fan Ma, Han Han, Dai-Yuan Li, Rong Fu, Qing-Yu Zhao, Ruiguo Wang, Dong-Sheng Guo*, Kang Cai*, Chem. Eur. J., 2025, 31, e202403271.
-
216
Supramolecular discrimination and diagnosis-guided treatment of intracellular bacteria, Jia-Hong Tian#, Siyuan Huang#, Ze-Han Wang, Juan-Juan Li, Xianhui Song, Ze-Tao Jiang, Bing-Sen Shi, Ying-Ying Zhao, Hui-Yan Zhang, Ke-Rang Wang, Xin-Yue Hu*, Xinge Zhang*, and Dong-Sheng Guo*, Nat. Commun., 2025, 16, 1016.
-
215
Assembly enhanced recognition: A biomimetic pathway to achieve ultrahigh affinities, Fang-Yuan Chen, Wen-Chao Geng, Meng-Meng Chen, Rong Fu, Han Han, Zhan-Zhan Zhang, Wen-Bo Li, Yuan-Qiu Cheng, Juan-Juan Li, J. Fraser Stoddart*, Kang Cai* and Dong-Sheng Guo*, Proc. Natl. Acad. Sci. U.S.A., 2025, 122, e2414253122.
-
214
Enhanced Subacute Ischemic Stroke Treatment via Multistage Drug Delivery System Design for Combination Therapy, Xihan Xu#, Juan-Juan Li#, Jiamin Li#, Hui-Yan Zhang, Yilin Qi, Bing-Sen Shi, Tianqi Li, Shan-Shan Su, Weitao Zhao, Chang Chen, Zhongying Gong, Huiyu Liu*, Ke-Rang Wang*, Dong-Sheng Guo* and Xue Xue*, Sci China Chem, 2025, 68, 3162–3174.
-
213
Broad-Spectrum Detoxification of Snake Venoms with Supramolecular Materials Integrated via Molecular Recognition and Coassembly, Meng-Meng Chen, Han-Wen Tian, Yuan-Qiu Cheng, Yu-Xin Yue, Yu-Chen Pan*, and Dong-Sheng Guo*, Adv. Healthc. Mater., 2025, 14, 2402732.
-
212
Ligand-Insertion Strategy for Constructing 2D Conjugated Metal-Organic Framework with Large Pore Size for Electrochemical Analytics, Xiu-Zhen Wang, Yue Chen, Xiao-Min Cao, Ru-Yi Li, Wei-Yan Chen, Yue Li*, and Dong-Sheng Guo, Angew. Chem. Int. Ed., 2025, 64, e202413115.
-
211
A Study of Chiral Biomedical Effects based on Macrocyclic Carriers, Ze-Han Wang#, Yuan-Qiu Cheng#, Wen-Bo Li, Meng-Meng Chen, Shu-Xin Zhang, Yu-Chen Pan*, Dong-Sheng Guo*, CCS Chem., 2025, 7, 2121–2136.
